Endotoxin tolerance represents a safeguard mechanism for preventing detrimental prolonged inflammation and exaggerated immune/inflammatory responses from innate immune cells to recurrent harmless pathogens.On the other hand, excessive immune tolerance can contribute to pathological immunosuppression, e.g., as present in sepsis.Monocyte activation i
Extensive cerebral and extracerebral metastases from a large-cell neuroendocrine cervical carcinoma
A 43 year-old woman, gravida 2 para 2 with no regular medical care, presented for 3 months of pelvic pain and vaginal bleeding.Pelvic examination revealed an 8-cm necrotic cervical mass.Biopsy of the lesion demonstrated high-grade large-cell neuroendocrine carcinoma (LCNEC) of the cervix.CT with contrast of chest, abdomen and pelvis showed extensiv
Avulsion of Ampulla of Vater Secondary to a Blunt Abdominal Injury Treated with Pancreatoduodenectomy; A Case Report and Literature Review
The incidence of complex hepatobiliary injury secondary to blunt abdominal injuries varies between 3.4 and 5%.A 25-year old male patient underwent an urgent operation due to a motorcycle accident.During intraabdominal exploration, Grade 4 laceration was detected at the liver and bleeding was controlled through primary repair.In the postoperative se
Exploring a framework for demandable services from antenatal to postnatal care: a deep-dive dialogue with mothers, health workers and psychologists
Abstract Background One of the factors affecting quality of care is that clients do not demand care practises during antenatal, intrapartum and postnatal care.This study aimed to identify care practices that can be demanded by the mother in the continuum of care from antenatal to postnatal.Methods The study respondents included 122 mothers, 31 heal